INVESTIGATIONS OF THE BINDING PARAMETRES OF THE INTERACTION OF N'-FERROCENYLMETHYL-N'-PHENYLACETO- AND PROPIONOHYDRAZIDE WITH DNA

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dc.contributor.authorMouada, H
dc.contributor.authorLanez, T
dc.contributor.authorLanez, E
dc.date.accessioned2023-05-29T10:08:29Z
dc.date.available2023-05-29T10:08:29Z
dc.date.issued2019-05-01
dc.descriptionarticleen_US
dc.description.abstractHerein we describe the determination of binding parameters of the interaction of N'- ferrocenylmethyl-N'-phenylacetohydrazide (FcA) and N'-ferrocenylmethyl-N'-phenylpropionohydrazide (FcP) derivatives with chicken blood double-stranded DNA (cb-ds DNA) in phosphate buffer (PB) solution at physiological pH 7.2 by electronic spectroscopy and molecular docking calculations. The results indicated that both FcA and FcP bind DNA in groove binding mode, values of binding constants and binding free energy obtained from electronic spectroscopy measurements and molecular docking calculations were in good agreementen_US
dc.identifier.citationH. Mouada, T. Lanez*, E. Lanez, INVESTIGATIONS OF THE BINDING PARAMETRES OF THE INTERACTION OF N'-FERROCENYLMETHYL-N'-PHENYLACETO- AND PROPIONOHYDRAZIDE WITH DNA. Journal of Fundamental and sciences. vol.11, no 2. May 2019. Faculty of exact sciences. university of el oued. [visited in 01/05/2019]. available from [[email protected]]en_US
dc.identifier.urihttp://dspace.univ-eloued.dz/handle/123456789/24732
dc.language.isoenen_US
dc.publisheruniversity of eloued -جامعة الواديen_US
dc.relation.ispartofseries1112-9867;
dc.subjectDNA, interaction, electronic spectroscopy, molecular dockingen_US
dc.titleINVESTIGATIONS OF THE BINDING PARAMETRES OF THE INTERACTION OF N'-FERROCENYLMETHYL-N'-PHENYLACETO- AND PROPIONOHYDRAZIDE WITH DNAen_US
dc.typeArticleen_US

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