JFAS_Vol 11 N 02

Permanent URI for this collectionhttps://dspace.univ-eloued.dz/handle/123456789/23349

Browse

Recent Submissions

Now showing 1 - 3 of 3
  • Thumbnail Image
    Item
    MOLECULAR DOKING AND ADMET STUDIES OF AMINO-PYRIMIDINE DERIVATIES AS MYCOBACTERIUM TUBERCULOSIS SER/THR PROTEIN KINASES B INHIBITORS
    (university of eloued -جامعة الوادي, 2019-05-01) Khamouli1, S; Belaidi, S; Lanez2, T
    We used the molecular docking method with Molegro software and we calculate ADME-T properties using Marvin Sketch and preADMET. The 29 amino-pyrimidines ligands were examined for docking studies with PknB (PDB Code: 2FUM).The Moldock score of the best three ligands L9, L12 and L21 are-161.475, -152.003 and-143.359 Kcal/Mol. These percentage shows that these candidature ligands have high binding energy percentage than the native MIX ligand. The ligand L21 has the human intestinal absorption (HIA), Caco-2 cell permeability, and plasma protein binding values of 85.48, 6.312 (nm/Sec.) and 93.097% respectively, which are comparable to MIX and the other ligands L9, L12. This computational study helped to prove that the ligand L21 have the ability to kill the Mycobacterium tuberculosis by inhibiting the expression of protein kinase B.
  • Thumbnail Image
    Item
    HIGH SENSITIVITY DETECTION OF THE STATOR SHORT-CIRCUIT FAULTS IN INDUCTION MOTOR USING HILBERT PARK’S VECTOR PRODUCT
    (university of eloued -جامعة الوادي, 2019-05-01) Allal, A; Chetate, B
    In this paper, a new approach for induction motor diagnosis, which called: Hilbert Park’s Vector Product Approach (HPVPA), is proposed, this processes offers unprecedented a high sensitivity in case of stator faults. In order to highlight the effectiveness of this method, this paper included with an important comparison between the proposed method and the proposed techniques in the recently research works; such as: Motor Square Current Signature Analysis (MSCSA), Park's Vector Square Modulus (PVSM), Park’s Vector Product Approach (PVPA), Park-Hilbert “P-H” ( PVSMP-H) and the classical method: Motor Current Signature Analysis (MCSA). The proposed approach bases on three essential steps: firstly, the Hilbert transform of the three phases currents will be aplicated, and then their instantaneous amplitudes will be extracted. Secondly,their current Park's vector components will be reduced. Finally, we apply the mathematical product of its two current Park’s vector components is applicated
  • Thumbnail Image
    Item
    GREEN SYNTHESIS OF IRON NANOPARTICULES USING LEAF EXTRACTFROMPHOENIX DACTYLIFERA. L
    (university of eloued -جامعة الوادي, 2019-05-01) Laouini, S.E
    In this research paper, the synthesis of ironnanoparticlesby a simple and eco-friendly methodusing extract leaves fromPhoenix DactyliferaL withdifferentconcentration ofFeCl3wasinvestigated. Thenanoparticlessynthesiswere characterizedusing adifferentmethodsUv-Visiblespectrophotometer, infraredspectroscopyandXRD. Thefirstresult was found forthe size ofnanoparticlesandrelationshipwiththeconcentration ofFeCl3, the highconcentration (0.03 M) product the nanoparticleswith size 2.3 nmand thelowconcentrationproduct thenanoparticles with size 22.16 nm. The FTIR analysisconfirmedthe biosynthesisofnanoparticleswith absorption from 500 to 800 cm-1. The crystallinestructureofNPswasconfirmed by X-ray diffraction (XRD) analysis. The antioxidant properties of the obtainedbiomaterial were assessedin vitro, using theDPPH and PPM test.The Fe3O4showed highantioxidant activity againstthemto test. Theresultssuggest thatPhoenix DactyliferaLextractassisted tosynthesisNPs present promising antioxidantcapacityand hence haveanimportant interestinthe development of therapeutic agents against oxidative tissue injuries.