Characterization Of Intestinal Microbiota In Celiac Children

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dc.contributor.authorLahcene, F.
dc.contributor.authorTir Touil Meddah, A.
dc.contributor.authorBouziane-nedjadi, K.
dc.contributor.authorMeddah, B.
dc.contributor.authorLeke, A.
dc.date.accessioned2020-10-28T08:51:41Z
dc.date.available2020-10-28T08:51:41Z
dc.date.issued2016-09-01
dc.descriptionArticale in Journal of fundamental and Applied Sciences Vol. 08, N. 03en_US
dc.description.abstractCeliac disease (CD) is enteropathy autoimmune induced by the ingestion of gluten in genetically predisposed subjects. The ingestion of gluten is responsible for the symptoms of CD, and a disturber of the intestinal microbiota. In this study, 13 Samples of intestinal biopsy, 15 fecal samples from celiac children, and 10 from controls children respectively were collected and analyzed by conventional culture technique to characterize the microbial profile intestinal of celiac children. There was 24 celiac children (8 boys), Mean age at diagnosis was 9.52 years, all have clinical manifestations, positive anti-transglutaminase antibodies and mucosal lesions suggestive of CD (Marsh Classification).We found a difference in intestinal microbiota, between celiac and controls children for example the Enterobacteria, Clostridium sp and Staphylococcus sp were remarkably higher in biopsy and fecal samples of celiac children than in controls. Inversely the Enterococcus sp, Lactobacillus sp and Clostridium sp were slightly lower in celiac children. Our results indicate an imbalance in intestinal microbiota for celiac children as reduction in the numbers of Lactobacillus sp, Enterococcus sp and increases in the numbers of Enterobacteria, Staphylococcus sp and Clostridium sp.en_US
dc.identifier.citationArticale in Journal of fundamental and Applied Sciences Vol. 08, N. 03en_US
dc.identifier.issn1112-9867
dc.identifier.urihttp://dspace.univ-eloued.dz/handle/123456789/7331
dc.language.isoenen_US
dc.publisherUniversity of Eloued جامعة الواديen_US
dc.subjectCeliac disease, Intestinal Microbiota, Anti-transglutaminase, Lacobacillus spen_US
dc.titleCharacterization Of Intestinal Microbiota In Celiac Childrenen_US
dc.typeArticleen_US

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