FREQUENCY AND COMPARISON OF SEROEPIDEMIOLOGY HSV AND CMV IN WOMEN WITH NATURAL CHILDBIRTH AND ABORTION IN SHAHID BEHESHTI HOSPITAL, ABADAN, IRAN

Abstract

Background: Cytomegalovirus and Herpes simplexvirus are one of the most common causes of congenital infections.

Objectives: The purpose of this study was to determine the seroprevalence of herpes simplex virus type 1 (HSV-1), type 2 (HSV-2) and CMV antibody in pregnant women admitting to antenatal care clinic of Shahid Beheshti Hospital in Abadan, Iran. Serum samples were collected during the study.

Methods: The enzyme-linked immunosorbent assay was used to detect anti-HSV-1, anti-HSV-2 type and anti- CMV. Socio-demographic and obstetric characteristics were used for further study.

Results: Between January and December 2016, we have studied 325 pregnant women referred to Shahid Beheshti Hospital. The mean of women’s age was 27.66 ± 5.96 years old (range 16 to 43 years). Of the 325 participants in this study, 40 (12.3 %) were HSV-1 seropositive, 78 (24%) were HSV-2 seropositive and 36 (11%) were CMV seropositive. A combined analysis was performed for HSV-1 and HSV-2: the percentages of individuals testing regarding both HSV-1 and HSV-2 negative, both HSV-1 and HSV-2 positive, were 207 (63.7%) and 4 (1.2%) respectively.