IJBAR_Vol 01 N 02
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Item Influence of salt stress on the mineral composition of Arthrospira platensis grown in an extreme environment in southern Algeria(University of Eloued جامعة الوادي, 2018-12-01) LAICHE, Ammar Touhami; BESSEI, AbdelmalekThe salinity of Saharan waters poses a problem for the growth of aquatic species. The cultivation of spirulina requires a culture medium with a salinity of about 13 g / l. The study consisted in the cultivation of spirulina in environments that differ in their salt content; D0: a control, D1: 13g / l, D2: 26g / l and D3: 39g / l. Daily reports of pH and electrical conductivity have been made. After obtaining the biomass, the determination of the level of certain spirulina mineral elements (Ca ++, Na + , K + , Mg ++, Fe ++) was carried out. According to the results, salinity does not seem to be a limiting factor for the growth of this species. Moreover, it seems that the salinity factor has little influence on the mineral composition of Spirulina, with a variability of pH values and electrical conductivity. Therefore, the cultivation of this species of seaweed in Saharan waters affected by a high salt content, seems possible and possibleItem Evaluation of total phenolic contents and antioxidant potentials of ten medicinal plants from Algerian Sahara(University of Eloued جامعة الوادي, 2018-12-01) DJAHRA, Ali Boutlelis; BENKADDOUR, Mounia; ZEGHIB, khaoula; BENKHERARA, Salah; OUALABI, Katrenada; GHANIA, Ahmed; JDIDI, KhaoulaIn the context of discovery a new antioxidants from natural sources. We are interested in this work to study the phenolic compounds and the antioxidant activities of aerial part extracts for ten (10) medicinal plants, from Wilaya of El-Oued (South-east Algeria) : Bassia muricata, Traganum nudatum, Haloxylon scoparium, Cornulaca monacantha, Malcolmia aegyptiaca, Retama raetam, Heliathemum lipii, Zygophyllum album, Ephedra alata, Moltkia ciliate . The results obtained demonstrated that phytochemical screening of aerial part extracts for ten plants studied varies from one plant species to another. The richness of Hiliantimum lippii and Retama raetam in polyphenols whose content varies between 134.67 and 133.33 mg AGE/g Ext respectively. For other plants, the polyphenol content is between 31.02 and 58.33 mg AGE/g Ext. The antioxidant activity tests by using the DPPH method show that all the extracts of the plants studied have antioxidant properties lower than ascorbic acid (IC50 = 16.25 μg / ml) of which the species Hiliantimum lippii represents the best capacity (IC50=27.79μg/ml). The low power is recorded in the species Haloxylon scoparium (IC50 = 793.29 μg / ml)Item Investigation of renal toxicity induced by neonicotinoid (thiamethoxam) insecticide in mice(University of Eloued جامعة الوادي, 2018-12-01) Saadi, Leila; Raki, Ahmed Aziz; Bouazza, MarwaThe investigation of the toxicity of a neonicotinoid insecticide, thiamethoxam, in mammals has been the subject of several experimental studies. In the present work, we are particularly interested in studying the renal toxic effects of two doses (0.2 and 0.4 mg/kg/day) of thiamethoxam, an insecticide widely marketed in Algeria, administered orally in adult male mice. For this purpose, a renal histopathological study and plasma assays of the uremia and the creatinemia are carried out. Examination of the histological sections recorded dose-dependent lesions in the renal parenchyma. Renal impairment is characterized by the destruction of certain glomeruli and the presence of some hemorrhagic and inflammatory foci. These alterations are associated with leukocyte diapedesis presented in the blood vessels. The renal function is maintained in the normal state because the urea and creatinine contents remain unchanged. On the basis of these results, it turns out that thiamethoxam treatment induces a dose-dependent renal toxicity in male mice.Item Evaluation of the effect of spinosad on lipid peroxidation and antioxidant markers in female mice(University of Eloued جامعة الوادي, 2018-12-01) Saadi, Leila1; Bouazza, Marwa; Mokrane, Ahlam; Aicha, Meriem; Lebaili, NemchaA Like any synthetic substance, or even natural, pesticides can produce harmful effects on human and animal health. The purpose of the present study is to evaluate the oxidative profile following the exposure of female mice to 9.2 mg/kg/day of spinosad. This is to examine the relationship between insecticide exposure and the risk of developing oxidative stress. Adult mice of the Naval Medical Research Institute were given by gavage daily for 18 days with spinosad, at rate of 9.2 mg/kg/day. Short-term exposure caused lipid auto-oxidation, expressed as an increase in malondialdehyde concentration in treated mice. Lipid peroxidation is associated with high level of plasma total anti-oxidative power and low level of plasma vitamin C. These results support the toxicity of the bioinsecticide witch induce oxidative stress in female miceItem Ameliorative effect of Aristolochia longa and Aquilariamalaccensison lead acetate inducednephrotoxicityin female rats(University of Eloued جامعة الوادي) DEROUICHE, Samir; GHARBI, Safa; ZEGHIB, Khaoula; KHELEF, YahiaBackground:Aquilariamalaccensis And Aristolochia longa are plants used extensively in traditional medicine for the treatment of cancer in several regions in Algeria. We investigate the ameliorative effect of Aristolochia longa and Aquilariamalaccensison kidney toxicity induced by lead in female albino rats. Methods:Twenty five (25) apparently healthy female Wistar rats were randomly divided into five groups of five rats in each: control, Pb, Pb + A. longa (Ar), Pb+ A. malaccensis (Aq), and Pb+Ar+Aq. lead (100 mg/kg b.w) as Pb(C2H3O2)2 added in their drinking water for 75 days. A. longa (rhizome powder at a dose 1% w/w of diet) and A. malaccensis (heartwood powder at a dose 1% w/w of diet) were added to the feed during the last 15 days of lead exposed in the animals. Results:Obtained results revealed that lead treatment caused a significant increase in blood glucose level, serum urea, creatinine and uric acidlevel and in kidneyof MDA level and CAT activity. In contrast, it led to an decrease in the kidneyGST activityand GSH level in rats .Also, the results clearly showed that lead causes alterations of glomerular and tubular structure in comparison with controls.Our results showed that treatment with A. malaccensis and A. longa a partial correction of the previous parameters.The histological observations confirmed the nephroprotection results by the biochemical parameters. Conclusion:Results demonstrated beneficial effects of A. longa and A. malaccensis treatment againacetate lead-induced toxicity and kidney damage in rats