Preliminary Screening for Antibacterial Activity of Endophytic Fungi isolated from Azadirachta indica and Mentha piperita against Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa
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Date
2022-12-30
Journal Title
Journal ISSN
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Publisher
جامعة الوادي - University of Eloued
Abstract
Endophytes have been identified as reservoirs of novel bioactive secondary metabolites that
can serve as a potential candidate for the development of new antimicrobial drugs. The aim of
the study was to screen for antibacterial activity of endophytic fungi isolated from Azadirachta
indica and Mentha piperita phyllosphere (healthy leaves). The endophytic fungi isolates were
screened for their antibacterial activity against Staphylococcus aureus, Escherichia coli and
Pseudomonas aeruginosa. Antibacterial activity of ethyl acetate extracts of the isolates was
also determined. A total 35 endophytic fungi were isolated out of which 11 showed
antibacterial activity against at least two of the test bacterial isolates. Ethyl acetate extracts of
these 11 endophytes had varying degree of antibacterial activity with zones of inhibition
ranging from 10±10 mm to 26±0.5 mm. Result of this study revealed that endophytic fungi
isolated leaves of A. indica and M. piperita produce bioactive compounds with antibacterial
activity against the test bacterial isolates.
Description
article
Keywords
endophytes, fungi, phyllosphere, Azadirachta indica, Mentha piperita, antibacterial.
Citation
.Ibrahim, Mohammed Hussaini, Halima Sadiya, Ahmed , Hauwa’u, Ahmad , Mamunu, Abdulkadir Sulaiman , Aisha, Usman . Preliminary Screening for Antibacterial Activity of Endophytic Fungi isolated from Azadirachta indica and Mentha piperita against Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa . Algerian Journal of Biosciences . Vol 03. N 02. 30/12/2022. University of Eloued .[Write down the date][Copy the download link ]