The Impact of Cerium Oxide Nanoparticles on Reactive Oxygen Species (ROS) Release Rate in Mice Organs
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Date
2023-06-30
Journal Title
Journal ISSN
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Publisher
Université of Eloued-جامعة الوادي
Abstract
The impact of exposing significant mouse organs to cerium oxide nanoparticles
(CeO2 NPs) has received considerable attention in the literature, but a comprehensive
review on this topic is lacking. This review aims to address this gap by examining the
influence of CeO2 NPs on the release rate of reactive oxygen species (ROS) in
various organs of mice. CeO2 NPs have demonstrated potential therapeutic
applications due to their ROS-scavenging abilities, which are relevant to oxidative
stress-related diseases. Recent studies investigating the effect of CeO2 NPs on ROS
release rate in organs such as the liver, spleen, lung, and brain are highlighted in this
article. The findings reveal a complex interaction between CeO2 NPs and the ROS
system, influenced by factors such as particle dose, size, and surface chemistry.
Furthermore, the impact of CeO2 NPs on ROS release rate is organ-specific and
dependent on the tissue microenvironment. The review also addresses the potential
toxicity of CeO2 NPs and emphasizes the need for further research to better
comprehend their mechanisms of action and long-term effects. By providing valuable
insights into the influence of CeO2 NPs on ROS release rate in mice organs, this
review holds significant implications for the therapeutic applications of CeO2 NPs in
oxidative stress-related diseases. This review contributes to the existing body of
knowledge by examining the impact of CeO2 NPs on ROS release rate in various
mouse organs.
Description
Keywords
Cerium oxide, oxidative stress, ROS, nanoparticles, mice organs, toxicity
Citation
Ikhazuagbe, Hilary Ifijen , Selina Ilunakan, Omonmhenle. The Impact of Cerium Oxide Nanoparticles on Reactive Oxygen Species (ROS) Release Rate in Mice Organs . Algerian Journal of Biosciences . Vol 04. N 01. 30/06/2023. University of Eloued .[Write down the date][Copy the download link ]