JFAS_Vol 03 N 02
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Browsing JFAS_Vol 03 N 02 by Subject "Butenolides , addition 1,6 reagents organocuprates, biological activity."
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Item The Synthesis Of (5-hydroxy-5-(1-methoxypropan-2-yl) -4-methylfuran-2(5h)-one, 5-(1-methoxypropan-2-yl) -4-methylfuran-2(5h)-one) And Biological Activity(University of Eloued جامعة الوادي, 2011-07-01) Gherraf, N.; Tamma, N.Butenolides are a class of lactones with a four carbon heterocyclic ring structure. They are sometimes considered as oxidized derivatives of furan. The simplest butenolide is 2-furanone, which is a common component of larger natural products and is sometimes referred to as simply "butenolide". A common biochemically important butenolide is ascorbic acid (vitamin C). The butenolide and their analogues represent a wide range of the natural compounds of medical and biological importance. In the last decades, a great number of compounds of various structures, in general from Alkylidene butenolide were isolated and showed biological activities. In this work we have studied the reactivity of some alkylidene butenolide and carried out their antibacterial activity.