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    SOLVENT EXTRACTIONSOLVENT EXTRACTION SOLVENT EXTRACTION SOLVENT EXTRACTIONSOLVENT EXTRACTIONSOLVENT EXTRACTION SOLVENT EXTRACTION SOLVENT EXTRACTION EFFECTS ON PHYTOCHEMICAL PROFILES, EFFECTS ON PHYTOCHEMICAL PROFILES, EFFECTS ON PHYTOCHEMICAL PROFILES, EFFECTS ON PHYTOCHEMICAL PROFILES, EFFECTS ON PHYTOCHEMICAL PROFILES, EFFECTS ON PHYTOCHEMICAL PROFILES, EFFECTS ON PHYTOCHEMICAL PROFILES, EFFECTS ON PHYTOCHEMICAL PROFILES, EFFECTS
    (university of eloued جامعة الوادي, 2020-09-01) C., . Boubékri1,2,*,; , . Koraichi3*, B.
    In this study,In this study, In this study, In this study, In this study, In this study, hexane and exane and exane and exane and exane and exane and ethanol were used separately as solvent in the extraction of different were used separately as solvent in the extraction of different were used separately as solvent in the extraction of different were used separately as solvent in the extraction of different were used separately as solvent in the extraction of different were used separately as solvent in the extraction of different were used separately as solvent in the extraction of different were used separately as solvent in the extraction of different were used separately as solvent in the extraction of different were used separately as solvent in the extraction of different were used separately as solvent in the extraction of different were used separately as solvent in the extraction of different were used separately as solvent in the extraction of different were used separately as solvent in the extraction of different were used separately as solvent in the extraction of different were used separately as solvent in the extraction of different were used separately as solvent in the extraction of different were used separately as solvent in the extraction of different were used separately as solvent in the extraction of different were used separately as solvent in the extraction of different were used separately as solvent in the extraction of different were used separately as solvent in the extraction of different were used separately as solvent in the extraction of different were used separately as solvent in the extraction of different were used separately as solvent in the extraction of different were used separately as solvent in the extraction of different were used separately as solvent in the extraction of different were used separately as solvent in the extraction of different part of fresh fruit part of fresh fruit part of fresh fruit part of fresh fruit part of fresh fruit ofpart of fresh fruit part of fresh fruit ofpart of fresh fruit part of fresh fruit Cucurbita pepoCucurbita pepo Cucurbita pepo Cucurbita pepo Cucurbita pepo Cucurbita pepo L. For each solvent, total phenolic content, For each solvent, total phenolic content, For each solvent, total phenolic content, For each solvent, total phenolic content, For each solvent, total phenolic content, For each solvent, total phenolic content, For each solvent, total phenolic content, For each solvent, total phenolic content, For each solvent, total phenolic content, For each solvent, total phenolic content, For each solvent, total phenolic content, For each solvent, total phenolic content, For each solvent, total phenolic content, For each solvent, total phenolic content, For each solvent, total phenolic content, For each solvent, total phenolic content, For each solvent, total phenolic content, total totaltotal flavonoid flavonoid content, total flavanol content and antioxidant activity in skin, pulp content, total flavanol content and antioxidant activity in skin, pulp content, total flavanol content and antioxidant activity in skin, pulp content, total flavanol content and antioxidant activity in skin, pulp content, total flavanol content and antioxidant activity in skin, pulp content, total flavanol content and antioxidant activity in skin, pulp content, total flavanol content and antioxidant activity in skin, pulp content, total flavanol content and antioxidant activity in skin, pulp content, total flavanol content and antioxidant activity in skin, pulp content, total flavanol content and antioxidant activity in skin, pulp content, total flavanol content and antioxidant activity in skin, pulp content, total flavanol content and antioxidant activity in skin, pulp content, total flavanol content and antioxidant activity in skin, pulp content, total flavanol content and antioxidant activity in skin, pulp content, total flavanol content and antioxidant activity in skin, pulp content, total flavanol content and antioxidant activity in skin, pulp content, total flavanol content and antioxidant activity in skin, pulp content, total flavanol content and antioxidant activity in skin, pulp content, total flavanol content and antioxidant activity in skin, pulp content, total flavanol content and antioxidant activity in skin, pulp content, total flavanol content and antioxidant activity in skin, pulp content, total flavanol content and antioxidant activity in skin, pulp content, total flavanol content and antioxidant activity in skin, pulp content, total flavanol content and antioxidant activity in skin, pulp content, total flavanol content and antioxidant activity in skin, pulp content, total flavanol content and antioxidant activity in skin, pulp whole fruit extract were inv whole fruit extract were invwhole fruit extract were inv whole fruit extract were inv whole fruit extract were invwhole fruit extract were invwhole fruit extract were inv whole fruit extract were invwhole fruit extract were invwhole fruit extract were inv whole fruit extract were inv whole fruit extract were inv whole fruit extract were invwhole fruit extract were invwhole fruit extract were inv estigated using stigated using stigated using stigated using stigated using in vitro vitro assays. The results showed that skin part is assays. The results showed that skin part is assays. The results showed that skin part is assays. The results showed that skin part is assays. The results showed that skin part is assays. The results showed that skin part is assays. The results showed that skin part is assays. The results showed that skin part is assays. The results showed that skin part is assays. The results showed that skin part is assays. The results showed that skin part is assays. The results showed that skin part is assays. The results showed that skin part is assays. The results showed that skin part is assays. The results showed that skin part is assays. The results showed that skin part is the rich one en compounds and ethanol is best solvent for extraction of total phenolics the rich one en compounds and ethanol is best solvent for extraction of total phenolics the rich one en compounds and ethanol is best solvent for extraction of total phenolics the rich one en compounds and ethanol is best solvent for extraction of total phenolics the rich one en compounds and ethanol is best solvent for extraction of total phenolics the rich one en compounds and ethanol is best solvent for extraction of total phenolics the rich one en compounds and ethanol is best solvent for extraction of total phenolics the rich one en compounds and ethanol is best solvent for extraction of total phenolics the rich one en compounds and ethanol is best solvent for extraction of total phenolics the rich one en compounds and ethanol is best solvent for extraction of total phenolics the rich one en compounds and ethanol is best solvent for extraction of total phenolics the rich one en compounds and ethanol is best solvent for extraction of total phenolics the rich one en compounds and ethanol is best solvent for extraction of total phenolics the rich one en compounds and ethanol is best solvent for extraction of total phenolics the rich one en compounds and ethanol is best solvent for extraction of total phenolics the rich one en compounds and ethanol is best solvent for extraction of total phenolics the rich one en compounds and ethanol is best solvent for extraction of total phenolics the rich one en compounds and ethanol is best solvent for extraction of total phenolics the rich one en compounds and ethanol is best solvent for extraction of total phenolics the rich one en compounds and ethanol is best solvent for extraction of total phenolics the rich one en compounds and ethanol is best solvent for extraction of total phenolics the rich one en compounds and ethanol is best solvent for extraction of total phenolics the rich one en compounds and ethanol is best solvent for extraction of total phenolics the rich one en compounds and ethanol is best solvent for extraction of total phenolics the rich one en compounds and ethanol is best solvent for extraction of total phenolics the rich one en compounds and ethanol is best solvent for extraction of total phenolics the rich one en compounds and ethanol is best solvent for extraction of total phenolics the rich one en compounds and ethanol is best solvent for extraction of total phenolics the rich one en compounds and ethanol is best solvent for extraction of total phenolics the rich one en compounds and ethanol is best solvent for extraction of total phenolics the rich one en compounds and ethanol is best solvent for extraction of total phenolics the rich one en compounds and ethanol is best solvent for extraction of total phenolics the rich one en compounds and ethanol is best solvent for extraction of total phenolics the rich one en compounds and ethanol is best solvent for extraction of total phenolics the rich one en compounds and ethanol is best solvent for extraction of total phenolics the rich one en compounds and ethanol is best solvent for extraction of total phenolics the rich one en compounds and ethanol is best solvent for extraction of total phenolics (231.16 mg (231.16 mg (231.16 mg GAE /g), total flavonoids (8,4 mg /g), total flavonoids (8,4 mg /g), total flavonoids (8,4 mg/g), total flavonoids (8,4 mg /g), total flavonoids (8,4 mg /g), total flavonoids (8,4 mg /g), total flavonoids (8,4 mg/g), total flavonoids (8,4 mg /g), total flavonoids (8,4 mg RE /g) and total fl/g) and total fl /g) and total fl/g) and total fl /g) and total fl /g) and total fl/g) and total fl /g) and total fl avanols (4,16 mgavanols (4,16 mg avanols (4,16 mg avanols (4,16 mg avanols (4,16 mg avanols (4,16 mg QE /g). For /g). For /g). For /g). For evaluation of antioxidant activity, using DPPH• radical scavenging and total valuation of antioxidant activity, using DPPH• radical scavenging and total valuation of antioxidant activity, using DPPH• radical scavenging and total valuation of antioxidant activity, using DPPH• radical scavenging and total valuation of antioxidant activity, using DPPH• radical scavenging and total valuation of antioxidant activity, using DPPH• radical scavenging and total valuation of antioxidant activity, using DPPH• radical scavenging and total valuation of antioxidant activity, using DPPH• radical scavenging and total valuation of antioxidant activity, using DPPH• radical scavenging and total valuation of antioxidant activity, using DPPH• radical scavenging and total valuation of antioxidant activity, using DPPH• radical scavenging and total valuation of antioxidant activity, using DPPH• radical scavenging and total valuation of antioxidant activity, using DPPH• radical scavenging and total valuation of antioxidant activity, using DPPH• radical scavenging and total valuation of antioxidant activity, using DPPH• radical scavenging and total valuation of antioxidant activity, using DPPH• radical scavenging and total valuation of antioxidant activity, using DPPH• radical scavenging and total valuation of antioxidant activity, using DPPH• radical scavenging and total valuation of antioxidant activity, using DPPH• radical scavenging and total valuation of antioxidant activity, using DPPH• radical scavenging and total valuation of antioxidant activity, using DPPH• radical scavenging and total valuation of antioxidant activity, using DPPH• radical scavenging and total valuation of antioxidant activity, using DPPH• radical scavenging and total valuation of antioxidant activity, using DPPH• radical scavenging and total valuation of antioxidant activity, using DPPH• radical scavenging and total valuation of antioxidant activity, using DPPH• radical scavenging and total valuation of antioxidant activity, using DPPH• radical scavenging and total valuation of antioxidant activity, using DPPH• radical scavenging and total valuation of antioxidant activity, using DPPH• radical scavenging and total valuation of antioxidant activity, using DPPH• radical scavenging and total valuation of antioxidant activity, using DPPH• radical scavenging and total valuation of antioxidant activity, using DPPH• radical scavenging and total valuation of antioxidant activity, using DPPH• radical scavenging and total valuation of antioxidant activity, using DPPH• radical scavenging and total activity, skin extract obtained by ethanol showed the highest value respectively (IC50= 0,42 activity, skin extract obtained by ethanol showed the highest value respectively (IC50= 0,42 activity, skin extract obtained by ethanol showed the highest value respectively (IC50= 0,42 activity, skin extract obtained by ethanol showed the highest value respectively (IC50= 0,42 activity, skin extract obtained by ethanol showed the highest value respectively (IC50= 0,42 activity, skin extract obtained by ethanol showed the highest value respectively (IC50= 0,42 activity, skin extract obtained by ethanol showed the highest value respectively (IC50= 0,42 activity, skin extract obtained by ethanol showed the highest value respectively (IC50= 0,42 activity, skin extract obtained by ethanol showed the highest value respectively (IC50= 0,42 activity, skin extract obtained by ethanol showed the highest value respectively (IC50= 0,42 activity, skin extract obtained by ethanol showed the highest value respectively (IC50= 0,42 activity, skin extract obtained by ethanol showed the highest value respectively (IC50= 0,42 activity, skin extract obtained by ethanol showed the highest value respectively (IC50= 0,42 activity, skin extract obtained by ethanol showed the highest value respectively (IC50= 0,42 activity, skin extract obtained by ethanol showed the highest value respectively (IC50= 0,42 activity, skin extract obtained by ethanol showed the highest value respectively (IC50= 0,42 activity, skin extract obtained by ethanol showed the highest value respectively (IC50= 0,42 activity, skin extract obtained by ethanol showed the highest value respectively (IC50= 0,42 activity, skin extract obtained by ethanol showed the highest value respectively (IC50= 0,42 activity, skin extract obtained by ethanol showed the highest value respectively (IC50= 0,42 activity, skin extract obtained by ethanol showed the highest value respectively (IC50= 0,42 activity, skin extract obtained by ethanol showed the highest value respectively (IC50= 0,42 activity, skin extract obtained by ethanol showed the highest value respectively (IC50= 0,42 activity, skin extract obtained by ethanol showed the highest value respectively (IC50= 0,42 activity, skin extract obtained by ethanol showed the highest value respectively (IC50= 0,42 activity, skin extract obtained by ethanol showed the highest value respectively (IC50= 0,42 activity, skin extract obtained by ethanol showed the highest value respectively (IC50= 0,42 activity, skin extract obtained by ethanol showed the highest value respectively (IC50= 0,42 activity, skin extract obtained by ethanol showed the highest value respectively (IC50= 0,42 activity, skin extract obtained by ethanol showed the highest value respectively (IC50= 0,42 activity, skin extract obtained by ethanol showed the highest value respectively (IC50= 0,42 activity, skin extract obtained by ethanol showed the highest value respectively (IC50= 0,42 activity, skin extract obtained by ethanol showed the highest value respectively (IC50= 0,42 activity, skin extract obtained by ethanol showed the highest value respectively (IC50= 0,42 activity, skin extract obtained by ethanol showed the highest value respectively (IC50= 0,42 mg/mL) and (19,72 g) mg/mL) and (19,72 g) mg/mL) and (19,72 g)mg/mL) and (19,72 g) mg/mL) and (19,72 g) mg/mL) and (19,72 g) mg/mL) and (19,72 g) mg/mL) and (19,72 g) . The superoxide scaven The superoxide scavenThe superoxide scaven The superoxide scaven The superoxide scavenThe superoxide scaven The superoxide scavenThe superoxide scaven The superoxide scavenging assay of ging assay of ging assay of ging assay of ethanol extracethanol extrac ethanol extracethanol extrac ethanol extrac ethanol extract of whole fruit whole fruit whole fruit whole fruit and skin showed the highest value respectively (ICand skin showed the highest value respectively (IC and skin showed the highest value respectively (IC and skin showed the highest value respectively (IC and skin showed the highest value respectively (ICand skin showed the highest value respectively (IC and skin showed the highest value respectively (IC and skin showed the highest value respectively (IC and skin showed the highest value respectively (ICand skin showed the highest value respectively (ICand skin showed the highest value respectively (IC and skin showed the highest value respectively (IC and skin showed the highest value respectively (IC and skin showed the highest value respectively (ICand skin showed the highest value respectively (IC50 = 0,015 mg/ml) and (0.016 ml)= 0,015 mg/ml) and (0.016 = 0,015 mg/ml) and (0.016 = 0,015 mg/ml) and (0.016 = 0,015 mg/ml) and (0.016 = 0,015 mg/ml) and (0.016 = 0,015 mg/ml) and (0.016 = 0,015 mg/ml) and (0.016 ml).