Bennouna, AB, BDendougui, H2023-05-292023-05-292019-05-01A.Bennouna1,2*, B.Labed2and H.Dendougui,Journal of Fundamental and Applied Sciencesis licensed under aCreative Commons Attribution-NonCommercial 4.0 International License.Libraries Resource Directory. We are listed underResearch Associationscategory.IN VITRO ANTIBACTERIAL ACTIVITY OF CHLOROFORM, ETHYL ACETATE AND BUTANOL EXTRACTS OF LEAVES OF CITRULLUS LANATUS VAR. CRIMSON SWEET GROWN IN THE REGION OF OUARGLA, ALGERIA . Journal of Fundamental and sciences. vol.11, no 2. May 2019. Faculty of exact sciences. university of el oued. [visited in 01/05/2019]. available from [bennounaab@mail.com]https://dspace.univ-eloued.dz/handle/123456789/24791articleWe are always trying to discover antibiotics, of natural origin, the most effective. For this purpose, our work is devoted to the evaluation of the antibacterial activity of the chloroformic, ethyl acetate and butanolic extracts of the leaves of citrulluslanatuscrimson sweet variety cultivated in the region of Ouargla. This activity was tested against microorganisms derived from the reference strains gram positive (Staphylococcus aureus and Streptococcus sp) and gram negative (Escherichia coli and Pseudomonas aeuruginosa). All extracts showed a remarkable sensitivity against bacteria by giving inhibition diameters varying between 12 and 26 mm. The evaluation of the minimum concentration of inhibition (MIC) led to the valuesbetween 40 and 75 μg/ml. From the results obtained, we can conclude that the leaves of this plant have a good antibacterial activity against certain microorganismsenCitrullus Lanatus var. Crimson sweet, antibacterial activity, CMI.Article