Bamigboye Bamigboye, Merc y OIkechukw u, POsunniran, Waha b AAdetunji, Juliana B2023-05-302023-05-302022-12-16Merc y O. Bamigboye Bamigboye1, Ikechukw u P. Ejidike, Waha b A. Osunniran, Juliana B. Adetunji , Joshu a A. Obaleye Catherin e A. Adenipekun, SYNTHESIS, CHARACTERIZATION, ANTIBACTERIAL AND TOXICOLOGICAL STUDIES OF HETEROLEPTIC ACETYLSALICYLIC ACID AND ANTHRANILIC ACID METAL COMPLEXES.Journal of Fundamental and Applied Sciences.VOL15 N01.16/12/2022.university of el oued [visited in ../../….]. available from [copy the link here]1112-9867http://dspace.univ-eloued.dz/handle/123456789/25141ArticleThis present study aims at evauating the antibacterial, analgesic, and toxicologic al activities of new metals [Ni(II), Cu(II), Cd(II), and Zn(II)] complexes deri v ed from acetylsalicylic acid and anthranilic acid via refluxing method in a 1:1:1 stoichiometry ratio. Characterization was executed using melting point, molar conductance, infrared and ultraviolet visible spectroscopies . The antibacterial activities were investigated by the agar well diffusion method. The toxicological effect of the test compounds in serum and kidney homogenates of Wister rats was investigated. The screened complexes showed better antibacterial activitie s than their free li gands. The resu l t of the analysis indicated that acetylsalicylic acid possessed a good significant analgesic activity, while toxicological studies confirmed that the complexes were toxic at the level of administered dosage.enA ntibacterial, Toxicology, Analgesic s , Anthranilic acid, Acetylsalicylic acidArticle